The fantastic Pazufloxacin mesilate

[nest]

In medicine, Pazufloxacin mesilate, whose CAS Number is 163680-77-1, is a total synthetic quinolone antibiotic used to treat diseases caused by a variety of bacterial infections. The clinical efficacy, safety and usefulness of Pazufloxacin mesilate, a new quinolone for injection, were evaluated in chronic respiratory tract infections in a comparative study versus ceftazidime (CAZ). As a rule, patients received either 500mg (as Pazufloxacin) of Pazufloxacin mesilate b.i.d. or 1,000mg (potency) of CAZ b.i.d., intravenously, for 14 days (28 vials). The following results were obtained in this trial. 1. A total of 203 patients were evaluated in this study, and 155 of them, were evaluated for clinical efficacy. Cases evaluated for adverse effects, abnormal laboratory findings, overall safety and usefulness numbered 185, 172, 177 and 153, respectively. 2. The clinical efficacy rate was 93.2% (68/73) in the Pazufloxacin mesilate (LookChemical) group and 91.5% (75/82) in the CAZ group. Both groups showed high efficacy. Since the 90% confidence interval of the efficacy rate difference between the two groups was -6.6-10.0%, clinical equivalency (non-inferiority) of the Pazufloxacin mesilate group to the CAZ group was demonstrated at .DELTA. =10%.